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Neuralink implanted a device in a human for the first time on Sunday=C2=
=A0


Sign Up [1]|Hire [2]|Advertise [3]|View Online [4]=20

=09=09=
TLDR=20

=09=09TOGETHER WITH [WorkOS] [5]

TLDR 2024-01-30

THE =
WORLD=E2=80=99S BEST LOGIN BOX IS HERE, AND IT=E2=80=99S BUILT ON OPEN SOUR=
CE
(SPONSOR) [5]=20

=F0=9F=86=95=C2=A0Meet Authkit by WorkOS [6]:
=
=E2=86=92 It=E2=80=99s compatible [5] with any app architecture. Easily syn=
c user
updates via realtime APIs.

=E2=86=92 It=E2=80=99s fully custo=
mizable [5] and fits natively with your app's
unique design.

=
=E2=86=92 It=E2=80=99s built on Radix [5], the most popular open source des= ign
system.

=E2=86=92 It supports all modern authentication standard=
s [5].

=E2=86=92 And best of all, it's free up to 1 million MAUs when =
used with
WorkOS User Management [7].

Your users, your data, maximum=
flexibility.

Discover AuthKit by WorkOS =E2=86=97=EF=B8=8F [5]

=
=F0=9F=93=B1=20

BIG TECH & STARTUPS

ELON MUSK=E2=80=99S NEURALINK =
IMPLANTS BRAIN TECH IN HUMAN PATIENT FOR THE
FIRST TIME (2 MINUTE READ) [=
8]=20

Neuralink implanted a device in a human for the first time on Sun=
day.
The patient is recovering well, according to a post on X by Elon Mus=
k.
Neuralink is developing a brain implant that aims to help patients
w=
ith severe paralysis control external technologies using only neural
sign=
als. The technology could help patients with severe degenerative
diseases=
communicate and interact with devices using their minds.
Neuralink has n=
ot disclosed how many human patients are involved in
its initial in-human=
trial.=20

APPLE HAS SOLD APPROXIMATELY 200,000 VISION PRO HEADSETS (1 =
MINUTE
READ) [9]=20

A source with knowledge of Apple's sales numbers =
says that the
company has sold more than 200,000 Vision Pro headsets. Pre=
-orders for
the headset began on January 19. Media reviews for the device=
are set
to go live today, so that could increase sales, and there is als=
o an
expected uptick in purchases after actual consumers begin sharing
=
hands-on experiences. Apple is prepared for a limited number of sales
due=
to the Vision Pro's niche market and high price tag.=20

=F0=9F=9A=80 =


SCIENCE & FUTURISTIC TECHNOLOGY

SCIENTISTS THINK THEY'RE ON THE=
VERGE OF BREACHING THE BLOOD-BRAIN
BARRIER (3 MINUTE READ) [10]=20

T=
he brain and spinal cord are well protected by the blood-brain
barrier, w=
hich stops almost all drugs from entering the central
nervous system. Res=
earchers at the University of Pennsylvania are
testing the delivery of li=
pid nanoparticles, fat-soluble packages that
can pass through the blood-b=
rain barrier and carry proteins,
antibodies, and messenger RNA with them.=
The technique is able to pass
some drugs through the blood-brain barrier=
, but not all of the
medicine made it into brain cells when tested in liv=
ing mice. The
researchers are using a new in vitro model that will help g=
uide the
future development of brain-targeted treatments.=20

SCIENTIS=
TS DOCUMENT FIRST-EVER TRANSMITTED ALZHEIMER=E2=80=99S CASES, TIED
TO NO-=
LONGER-USED MEDICAL PROCEDURE (8 MINUTE READ) [11]=20

A decades-old tre=
atment for a number of conditions that caused short
stature, which involv=
ed patients receiving growth hormone taken from
the brains of human cadav=
ers, has been tied to some people as young as
in their 30s developing Alz=
heimer's disease. The treatment, which was
banned 40 years ago, transmitt=
ed unwanted proteins into recipients'
brains, including the beta-amyloid =
protein that later propagated into
the disease-causing plaques that are t=
he hallmark of the disease.
These are the first documented cases of trans=
ferred Alzheimer's - the
disease is not usually contagious. The cadaveric=
growth hormone
treatment has been long replaced with a synthetic hormone=
treatment.=20

=F0=9F=92=BB=20

PROGRAMMING, DESIGN & DATA SCIENCE
=

THE BIG LITTLE GUIDE TO MESSAGE QUEUES (40 MINUTE READ) [12]=20

Mes=
sage queues are a way to transfer information between two systems.
They a=
llow systems to communicate with each other in structured ways
they can b=
oth understand and at a controlled speed they can both
handle. This artic=
le discusses message queues, their history, why
they're useful, how they =
work, and more. It compares many popular
systems available today. The art=
icle covers fundamental concepts that
underlie message queues and how the=
y apply to popular queuing systems
available today.=20

NEW GITHUB COP=
ILOT RESEARCH FINDS 'DOWNWARD PRESSURE ON CODE QUALITY'
(4 MINUTE READ) [=
13]=20

A recent study on the quality and maintainability of AI-assisted=
code
found disconcerting trends for maintainability. The percentage of=

lines that are reverted or updated less than two weeks after being
aut=
hored is projected to double this year compared to a pre-AI
baseline. Usi=
ng AI coding tools is strongly correlated with mistake
code being pushed =
to repositories. While AI may be able to produce
code faster, the code it=
produces needs to be cleaned up, potentially
removing the benefits of fa=
st code generation.=20

=F0=9F=8E=81=20

MISCELLANEOUS

WHAT BIG T=
ECH LAYOFFS SUGGEST FOR THE INDUSTRY (7 MINUTE READ) [14]=20

Microsoft'=
s layoffs last year were worrisome because the company has
a very good tr=
ack record of predicting how its business will grow or
shrink. Microsoft'=
s business is incredibly diversified to the point
where it can be pretty =
representative of the B2B tech industry, minus
advertising. The company's=
decision to initiate layoffs suggested that
the tech industry would stal=
l growth-wise. Microsoft's announcements
could have caused other large te=
ch companies to follow suit and
announce their own layoffs.=20

STARLI=
NK'S LATEST OFFERING: GIGABIT GATEWAYS STARTING AT $75,000 PER
MONTH (2 M=
INUTE READ) [15]=20

Starlink's latest new Community Gateways service fo=
r internet service
providers can deliver gigabit speeds. For $1.25 millio=
n up front (and
$75,000 per month), customers will receive help to build =
an entire
facility dedicated to receiving up to 10Gbps in broadband speed=
s. ISPs
will need to provide the land, power, and lifting equipment. The =
first
Community Gateway was built on an island near Alaska. Pictures from=

the Community Gateway are available in the article.=20

=E2=9A=A1=20
=

QUICK LINKS

IT TURNS OUT NASA=E2=80=99S MARS HELICOPTER WAS MUCH M=
ORE REVOLUTIONARY
THAN WE KNEW (4 MINUTE READ) [16]=20

Ingenuity demo=
nstrated that powered flight is possible on other
planets, forever changi=
ng the way humans will explore and settle other
worlds.=20

META RELEA=
SES =E2=80=98CODE LLAMA 70B=E2=80=99, AN OPEN-SOURCE BEHEMOTH TO RIVAL
PR=
IVATE AI DEVELOPMENT (4 MINUTE READ) [17]=20

Code Llama 70B, one of the=
largest open-source AI models for code
generation currently available, w=
as trained on 500 billion tokens of
code and code-related data and has a =
context window of 100,000 tokens.


GOOGLE SIGNIFICANTLY REDUCES REC=
APTCHA FREE TIER, INTRODUCES NEW
PRICING MODELS (1 MINUTE READ) [18]=20
=

Starting from April 1, Google's previous free reCAPTCHA service will
=
be reduced from 1 million assessments to just 10,000 per month - a new
re=
CAPTCHA standard plan will be introduced with 100,000 assessments
for $8 =
per month.=20

TAKE THE ROAD MOST DOCUMENTED (2 MINUTE READ) [19]=20

=
Popular software is not always the most understandable - choosing
progra=
ms with extensive documentation and active community resources
makes solv=
ing problems much easier.=20

AMAZON ABANDONS $1.4 BILLION DEAL TO BUY R=
OOMBA MAKER IROBOT (2
MINUTE READ) [20]=20

The deal has no path to re=
gulatory approval in the EU.=20

TIKTOK GOES FULL YOUTUBE (1 MINUTE READ=
) [21]=20

TikTok will boost horizontal videos that are more than a minu=
te long
within 72 hours of posting for creators who have been on the plat=
form
for more than three months, as long as the videos are not ads or fro=
m
political parties.=20

WANT THE BEST OF TLDR? =F0=9F=8F=86

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a friend to TLDR using the referral link below, and we will send
you the=
TLDR Hall of Fame, our 50 best stories of all time!

YOUR REFERRAL LIN=
K - https://tldr.tech/tech?ref=3D6061602 [22]

WANT MORE TLDR?

We =
also write newsletters for FOUNDERS [23], AI [24], INFORMATION
SECURITY [=
25], DESIGN [26], MARKETING [27], CRYPTO [28], WEB DEV [29],
PRODUCT [30]=
, and DEVOPS [31]!

We help cutting edge companies hire world class te=
chnical talent
through our job listings. If you're hiring software engine=
ers, AI/ML
engineers, product managers, designers or other tech talent, C=
LICK
HERE TO LEARN MORE [2].=20

If your company is interested in reach=
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ack, just respond to this email!=20

Thanks for reading,=20
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Links:=

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[8] https= ://www.cnbc.com/2024/01/29/elon-musks-neuralink-implants-brain-tech-in-huma= n-patient-for-the-first-time.html?utm_source=3Dtldrnewsletter
[9] https:/= /www.macrumors.com/2024/01/29/apple-vision-pro-headset-sales/?utm_source=3D= tldrnewsletter
[10] https://www.sciencealert.com/scientists-think-theyre-= on-the-verge-of-breaching-the-blood-brain-barrier?utm_source=3Dtldrnewslett=
er
[11] https://www.statnews.com/2024/01/29/first-transmitted-alzheimers-= disease-cases-growth-hormone-cadavers/?utm_source=3Dtldrnewsletter
[12] h= ttps://sudhir.io/the-big-little-guide-to-message-queues?utm_source=3Dtldrne= wsletter
[13] https://visualstudiomagazine.com/articles/2024/01/25/copilo= t-research.aspx?utm_source=3Dtldrnewsletter
[14] https://blog.pragmaticen= gineer.com/the-scoop-big-tech-layoffs/?utm_source=3Dtldrnewsletter
[15] h= ttps://www.pcmag.com/news/starlinks-latest-offering-gigabit-gateways-starti= ng-at-75000-per-month?utm_source=3Dtldrnewsletter
[16] https://arstechnic= a.com/space/2024/01/now-that-weve-flown-on-mars-what-comes-next-in-aerial-p= lanetary-exploration/?utm_source=3Dtldrnewsletter
[17] https://venturebea= t.com/ai/meta-releases-code-llama-70b-an-open-source-behemoth-to-rival-priv= ate-ai-development/?utm_source=3Dtldrnewsletter
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<div style=3D"display:none; font-size:0px; line-height:0px; max-height:0px;=
max-width:0px; opacity:0; overflow:hidden; visibility:hidden; mso-hide:all= ;">Neuralink implanted a device in a human for the first time on Sunday&nbs= p;</div>


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<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"text-= align: center;"><span data-darkreader-inline-color=3D"" style=3D"--darkread= er-inline-color:#3db3ff; color: rgb(51, 175, 255) !important; font-size: 30= px;">T</span><span style=3D"font-size: 30px;"><span data-darkreader-inline-= color=3D"" style=3D"color: rgb(232, 192, 96) !important; --darkreader-inlin= e-color:#e8c163; font-size:30px;">L</span><span data-darkreader-inline-colo= r=3D"" style=3D"color: rgb(101, 195, 173) !important; --darkreader-inline-c= olor:#6ec7b2; font-size:30px;">D</span></span><span data-darkreader-inline-= color=3D"" style=3D"--darkreader-inline-color:#dd6e6e; color: rgb(220, 107,=
107) !important; font-size: 30px;">R</span>

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<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr id=3D"together-with"><td align=3D"cent= er" height=3D"20" style=3D"vertical-align:middle !important;" valign=3D"mid= dle" width=3D"100%"><strong style=3D"vertical-align:middle !important; heig= ht: 100%;">Together With </strong><a href=3D"https://tracking.tldrnewslette= r.com/CL0/https:%2F%2Fwww.authkit.com%2F%3Futm_source=3Dtldr%26utm_medium= =3Dnewsletter%26utm_campaign=3Dq12024/1/0100018d5a2987da-7e6d9381-accb-4cbd= -8515-d5cfce63bcef-000000/Rhb_hTBfYdTsn2qgm0-lN4jg49ZSUuSRu1lqBxD3538=3D338= "><img src=3D"https://jwwrbzsvyukwfpbuimxf.supabase.co/storage/v1/object/pu= blic/sponsor-logos/workos.png?t=3D2024-01-30T08%3A56%3A31.457Z" valign=3D"m= iddle" style=3D"vertical-align: middle !important; height: 100%;" alt=3D"Wo= rkOS"></a></td></tr></tbody></table>

<table style=3D"table-layout: fixed; width:100%;" width=3D"100%"><tbody><tr= ><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0;=

<div style=3D"text-align: center;">

<h3><strong>TLDR <span id=3D"date">2024-01-30</span></strong></h3>
</div>
</td></tr>
<tr id=3D"sponsy-copy"><td class=3D"container" style=3D"padding: 15px 15px;= ">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.authkit.com%2F%3Futm_source=3Dtldr%26utm_medium=3Dn= ewsletter%26utm_campaign=3Dq12024/2/0100018d5a2987da-7e6d9381-accb-4cbd-851= 5-d5cfce63bcef-000000/b0GBxMQ5iqvSu-Y9cdyPsBfZAWAY6dpBCWyziefyl5M=3D338">
<span>
<strong>The world=E2=80=99s best lo= gin box is here, and it=E2=80=99s built on open source (Sponsor)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
=F0=9F=86=95&nbsp;Meet <a href=3D"https= ://tracking.tldrnewsletter.com/CL0/https:%2F%2Fwww.authkit.com%2F%3Futm_sou= rce=3Dtldr-tech%26utm_campaign=3D20243001/1/0100018d5a2987da-7e6d9381-accb-= 4cbd-8515-d5cfce63bcef-000000/Rpzjsa4pYyGSe0FSJhY4lo04ZfrWq86UpCGDb4s_8Qk= =3D338" rel=3D"noopener noreferrer nofollow" target=3D"_blank"><span>Authki=
t by WorkOS</span></a>:<p>=E2=86=92 It=E2=80=99s <a href=3D"https://trackin= g.tldrnewsletter.com/CL0/https:%2F%2Fwww.authkit.com%2F%3Futm_source=3Dtldr= %26utm_medium=3Dnewsletter%26utm_campaign=3Dq12024/3/0100018d5a2987da-7e6d9= 381-accb-4cbd-8515-d5cfce63bcef-000000/pZ-qUMi9gPVEwYjzxfO4SPjLrWfCWDAcc0Or= 2471Jgg=3D338" rel=3D"noopener noreferrer nofollow" target=3D"_blank"><span= >compatible</span></a> with any app architecture. Easily sync user updates = via realtime APIs.</p><p>=E2=86=92 It=E2=80=99s fully <a href=3D"https://tr= acking.tldrnewsletter.com/CL0/https:%2F%2Fwww.authkit.com%2F%3Futm_source= =3Dtldr%26utm_medium=3Dnewsletter%26utm_campaign=3Dq12024/4/0100018d5a2987d= a-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/ghzwBrCAb6c_jyVSVAUDZ8nnU54eJ= uxqsUkkjtukayU=3D338" rel=3D"noopener noreferrer nofollow" target=3D"_blank= "><span>customizable</span></a> and fits natively with your app's unique de= sign.</p><p>=E2=86=92 It=E2=80=99s <a href=3D"https://tracking.tldrnewslett= er.com/CL0/https:%2F%2Fwww.authkit.com%2F%3Futm_source=3Dtldr%26utm_medium= =3Dnewsletter%26utm_campaign=3Dq12024/5/0100018d5a2987da-7e6d9381-accb-4cbd= -8515-d5cfce63bcef-000000/Pl0U8YHj22JsCijUZba8Z5oIOQO2-aj-8hRkhY9lDsc=3D338=
" rel=3D"noopener noreferrer nofollow" target=3D"_blank"><span>built on Rad= ix</span></a>, the most popular open source design system.</p><p>=E2=86=92 =
It supports all <a href=3D"https://tracking.tldrnewsletter.com/CL0/https:%2= F%2Fwww.authkit.com%2F%3Futm_source=3Dtldr%26utm_medium=3Dnewsletter%26utm_= campaign=3Dq12024/6/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-0= 00000/xtMOXCsOz5LSzsASFzICVQeNQu166eAtdfal1Jd4LTg=3D338" rel=3D"noopener no= referrer nofollow" target=3D"_blank"><span>modern authentication standards<= /span></a>.</p><p>=E2=86=92 And best of all, it's free up to 1 million MAUs=
when used with <a href=3D"https://tracking.tldrnewsletter.com/CL0/https:%2= F%2Fworkos.com%2Fuser-management/1/0100018d5a2987da-7e6d9381-accb-4cbd-8515= -d5cfce63bcef-000000/4KjHdS4rZCSHApCf_0yU8kOFYLEFxp_mTgfZtf-z1Bw=3D338" rel= =3D"noopener noreferrer nofollow" target=3D"_blank"><span>WorkOS User Manag= ement</span></a>.</p><p>Your users, your data, maximum flexibility.</p><p><=
a href=3D"https://tracking.tldrnewsletter.com/CL0/https:%2F%2Fwww.authkit.c= om%2F%3Futm_source=3Dtldr%26utm_medium=3Dnewsletter%26utm_campaign=3Dq12024= /7/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/HVmXoZm8_fY= Vgz9vFmDIsiTai49zqJb-_6gnnpcPQ0k=3D338" rel=3D"noopener noreferrer nofollow=
" target=3D"_blank"><span>Discover AuthKit by WorkOS =E2=86=97=EF=B8=8F</sp= an></a>
=20
=20
</p></span></span></div>=20
</td></tr></tbody></table>


</td></tr></tbody></table>
</td></tr></tbody></table>
</td></tr>
<tr bgcolor=3D""><td class=3D"container">

<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td style=3D"padding: 0px;">

<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =93=B1</span></div></div>
</td></tr></tbody></table>

<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;">

<h3><strong>Big Tech &amp; Startups</strong></h3>
</div>
</div>
</td></tr></tbody></table>

<table style=3D"table-layout: fixed; width: 100%;" width=3D"100%"><tbody><t= r><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0=
;" valign=3D"top"><table align=3D"center" border=3D"0" cellpadding=3D"0" ce= llspacing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"= padding: 15px 15px;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.cnbc.com%2F2024%2F01%2F29%2Felon-musks-neuralink-im= plants-brain-tech-in-human-patient-for-the-first-time.html%3Futm_source=3Dt= ldrnewsletter/1/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-00000= 0/Vc1sVNcjvNaCOfDueHdd1RQJ-Co25UL70v9kiGLyu2Q=3D338">
<span>
<strong>Elon Musk=E2=80=99s Neurali=
nk implants brain tech in human patient for the first time (2 minute read)<= /strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Neuralink implanted a device in a human=
for the first time on Sunday. The patient is recovering well, according to=
a post on X by Elon Musk. Neuralink is developing a brain implant that aim=
s to help patients with severe paralysis control external technologies usin=
g only neural signals. The technology could help patients with severe degen= erative diseases communicate and interact with devices using their minds. N= euralink has not disclosed how many human patients are involved in its init= ial in-human trial.
</span>
</span>
</div>=20
</td></tr></tbody></table>

<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.macrumors.com%2F2024%2F01%2F29%2Fapple-vision-pro-h= eadset-sales%2F%3Futm_source=3Dtldrnewsletter/1/0100018d5a2987da-7e6d9381-a= ccb-4cbd-8515-d5cfce63bcef-000000/l96zj6faDqw9DJX1mr1Ugu3FWffItvZoW-5pXEEdd= aE=3D338">
<span>
<strong>Apple Has Sold Approximatel=
y 200,000 Vision Pro Headsets (1 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
A source with knowledge of Apple's sale=
s numbers says that the company has sold more than 200,000 Vision Pro heads= ets. Pre-orders for the headset began on January 19. Media reviews for the = device are set to go live today, so that could increase sales, and there is=
also an expected uptick in purchases after actual consumers begin sharing = hands-on experiences. Apple is prepared for a limited number of sales due t=
o the Vision Pro's niche market and high price tag.
</span>
</span>
</div>=20
</td></tr></tbody></table>

</td></tr></tbody></table>


<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =9A=80</span></div>
</div>
</td></tr></tbody></table>

<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;">

<h3><strong>Science &amp; Futuristic Technology</strong></h3>
</div>
</div>
</td></tr></tbody></table>

<table style=3D"table-layout: fixed; width: 100%;" width=3D"100%"><tbody><t= r><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0=
;" valign=3D"top"><table align=3D"center" border=3D"0" cellpadding=3D"0" ce= llspacing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"= padding: 15px 15px;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.sciencealert.com%2Fscientists-think-theyre-on-the-v= erge-of-breaching-the-blood-brain-barrier%3Futm_source=3Dtldrnewsletter/1/0= 100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/eK7qUXBvR9SulAD= pauIN0pcBbEG8vgw5UEPRS6LqJUM=3D338">
<span>
<strong>Scientists Think They're on=
The Verge of Breaching The Blood-Brain Barrier (3 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
The brain and spinal cord are well prot= ected by the blood-brain barrier, which stops almost all drugs from enterin=
g the central nervous system. Researchers at the University of Pennsylvania=
are testing the delivery of lipid nanoparticles, fat-soluble packages that=
can pass through the blood-brain barrier and carry proteins, antibodies, a=
nd messenger RNA with them. The technique is able to pass some drugs throug=
h the blood-brain barrier, but not all of the medicine made it into brain c= ells when tested in living mice. The researchers are using a new in vitro m= odel that will help guide the future development of brain-targeted treatmen= ts.
</span>
</span>
</div>=20
</td></tr></tbody></table>

<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.statnews.com%2F2024%2F01%2F29%2Ffirst-transmitted-a= lzheimers-disease-cases-growth-hormone-cadavers%2F%3Futm_source=3Dtldrnewsl= etter/1/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/CRGxyh= mr2Ax3_1r2E__kAb_u0xzqTPWwZkbzQKHzXbI=3D338">
<span>
<strong>Scientists document first-e= ver transmitted Alzheimer=E2=80=99s cases, tied to no-longer-used medical p= rocedure (8 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
A decades-old treatment for a number of=
conditions that caused short stature, which involved patients receiving gr= owth hormone taken from the brains of human cadavers, has been tied to some=
people as young as in their 30s developing Alzheimer's disease. The treatm= ent, which was banned 40 years ago, transmitted unwanted proteins into reci= pients' brains, including the beta-amyloid protein that later propagated in=
to the disease-causing plaques that are the hallmark of the disease. These = are the first documented cases of transferred Alzheimer's - the disease is = not usually contagious. The cadaveric growth hormone treatment has been lon=
g replaced with a synthetic hormone treatment.
</span>
</span>
</div>=20
</td></tr></tbody></table>

</td></tr></tbody></table>


<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =92=BB</span></div></div>
</td></tr></tbody></table>

<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;">

<h3><strong>Programming, Design &amp; Data Science</strong></h3>
</div>
</div>
</td></tr></tbody></table>

<table style=3D"table-layout: fixed; width: 100%;" width=3D"100%"><tbody><t= r><td style=3D"padding:0;border-collapse:collapse;border-spacing:0;margin:0=
;" valign=3D"top"><table align=3D"center" border=3D"0" cellpadding=3D"0" ce= llspacing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"= padding: 15px 15px;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fsudhir.io%2Fthe-big-little-guide-to-message-queues%3Fut= m_source=3Dtldrnewsletter/1/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce= 63bcef-000000/rqQY-3Elza02quxovvCVYYTfp6uW0aUyzQQqi-nAJRA=3D338">
<span>
<strong>The Big Little Guide to Mes= sage Queues (40 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Message queues are a way to transfer in= formation between two systems. They allow systems to communicate with each = other in structured ways they can both understand and at a controlled speed=
they can both handle. This article discusses message queues, their history=
, why they're useful, how they work, and more. It compares many popular sys= tems available today. The article covers fundamental concepts that underlie=
message queues and how they apply to popular queuing systems available tod= ay.
</span>
</span>
</div>=20
</td></tr></tbody></table>

<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fvisualstudiomagazine.com%2Farticles%2F2024%2F01%2F25%2F= copilot-research.aspx%3Futm_source=3Dtldrnewsletter/1/0100018d5a2987da-7e6d= 9381-accb-4cbd-8515-d5cfce63bcef-000000/6Sr82tonWVPD-GqYfVlVxKvyHxQ7jqdBehr= R_8rC0yQ=3D338">
<span>
<strong>New GitHub Copilot Research=
Finds 'Downward Pressure on Code Quality' (4 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
A recent study on the quality and maint= ainability of AI-assisted code found disconcerting trends for maintainabili= ty. The percentage of lines that are reverted or updated less than two week=
s after being authored is projected to double this year compared to a pre-A=
I baseline. Using AI coding tools is strongly correlated with mistake code = being pushed to repositories. While AI may be able to produce code faster, = the code it produces needs to be cleaned up, potentially removing the benef= its of fast code generation.
</span>
</span>
</div>=20
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</td></tr></tbody></table>



<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=F0=9F= =8E=81</span></div></div>
</td></tr></tbody></table>

<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;"><strong><h3>Miscellaneous</h3></strong><= /div>
</div>
</td></tr></tbody></table>

<table bgcolor=3D"" style=3D"table-layout: fixed; width: 100%;" width=3D"10= 0%"><tbody><tr><td style=3D"padding:0;border-collapse:collapse;border-spaci= ng:0;margin:0;" valign=3D"top"><table align=3D"center" border=3D"0" cellpad= ding=3D"0" cellspacing=3D"0" width=3D"100%"><tbody><tr><td class=3D"contain= er" style=3D"padding: 15px 15px;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fblog.pragmaticengineer.com%2Fthe-scoop-big-tech-layoffs= %2F%3Futm_source=3Dtldrnewsletter/1/0100018d5a2987da-7e6d9381-accb-4cbd-851= 5-d5cfce63bcef-000000/uYjvHlzKr-gA_yWenfiJ_FqKdayHSUmu0yFXiUsHOc0=3D338">
<span>
<strong>What Big Tech layoffs sugge=
st for the industry (7 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Microsoft's layoffs last year were worr= isome because the company has a very good track record of predicting how it=
s business will grow or shrink. Microsoft's business is incredibly diversif= ied to the point where it can be pretty representative of the B2B tech indu= stry, minus advertising. The company's decision to initiate layoffs suggest=
ed that the tech industry would stall growth-wise. Microsoft's announcement=
s could have caused other large tech companies to follow suit and announce = their own layoffs.
</span>
</span>
</div>=20
</td></tr></tbody></table>

<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
<div class=3D"text-block">
<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.pcmag.com%2Fnews%2Fstarlinks-latest-offering-gigabi= t-gateways-starting-at-75000-per-month%3Futm_source=3Dtldrnewsletter/1/0100= 018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/TJHkjtomGSx8LDoKfF= 2YTA-GSI9bJUDrqfUge7axnUI=3D338">
<span>
<strong>Starlink's Latest Offering:=
Gigabit Gateways Starting at $75,000 Per Month (2 minute read)</strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Starlink's latest new Community Gateway=
s service for internet service providers can deliver gigabit speeds. For $1= .25 million up front (and $75,000 per month), customers will receive help t=
o build an entire facility dedicated to receiving up to 10Gbps in broadband=
speeds. ISPs will need to provide the land, power, and lifting equipment. = The first Community Gateway was built on an island near Alaska. Pictures fr=
om the Community Gateway are available in the article.
</span>
</span>
</div>=20
</td></tr></tbody></table>

</td></tr></tbody></table>


<table align=3D"center" bgcolor=3D"" border=3D"0" cellpadding=3D"0" cellspa= cing=3D"0" width=3D"100%"><tbody><tr><td class=3D"container" style=3D"paddi= ng-top: 0px; padding-bottom: 0px;">
<div class=3D"text-block">
<div style=3D"text-align: center;"><span style=3D"font-size: 36px;">=E2=9A= =A1</span></div></div>
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<div style=3D"text-align: center;">

<h3><strong>Quick Links</strong></h3>
</div>
</div>
</td></tr></tbody></table>

<table bgcolor=3D"" style=3D"table-layout: fixed; width: 100%;" width=3D"10= 0%"><tbody><tr><td style=3D"padding:0;border-collapse:collapse;border-spaci= ng:0;margin:0;" valign=3D"top"><table align=3D"center" border=3D"0" cellpad= ding=3D"0" cellspacing=3D"0" width=3D"100%"><tbody><tr><td class=3D"contain= er" style=3D"padding: 15px 15px;">=20
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<strong>It turns out NASA=E2=80=99s=
Mars helicopter was much more revolutionary than we knew (4 minute read)</= strong>
</span>
</a>
<br><br>
<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Ingenuity demonstrated that powered fli= ght is possible on other planets, forever changing the way humans will expl= ore and settle other worlds.
</span>
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</div>=20
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<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
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<span>
<strong>Meta releases =E2=80=98Code=
Llama 70B=E2=80=99, an open-source behemoth to rival private AI developmen=
t (4 minute read)</strong>
</span>
</a>
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<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Code Llama 70B, one of the largest open= -source AI models for code generation currently available, was trained on 5=
00 billion tokens of code and code-related data and has a context window of=
100,000 tokens.
</span>
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</div>=20
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<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
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<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fbytepursuits.com%2Fgoogle-significantly-reduces-recaptc= ha-free-tier-introduces-new-pricing-models%3Futm_source=3Dtldrnewsletter/1/= 0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/JjXCM7I9hMIUvD= vP-j1E0hDM0sDP3IM3NwqUmwTZ2QM=3D338">
<span>
<strong>Google significantly reduce=
s recaptcha free tier, introduces new pricing models (1 minute read)</stron=

</span>
</a>
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<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Starting from April 1, Google's previou=
s free reCAPTCHA service will be reduced from 1 million assessments to just=
10,000 per month - a new reCAPTCHA standard plan will be introduced with 1= 00,000 assessments for $8 per month.
</span>
</span>
</div>=20
</td></tr></tbody></table>

<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
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<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fjarbus.net%2Fblog%2Ftake-the-road-most-documented%2F%3F= utm_source=3Dtldrnewsletter/1/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cf= ce63bcef-000000/XJyR6Uqzlq6eoxw_Jx-iPtyB34OB_37xGt4kG9ArWOc=3D338">
<span>
<strong>Take the Road Most Document=
ed (2 minute read)</strong>
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</a>
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<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
Popular software is not always the most=
understandable - choosing programs with extensive documentation and active=
community resources makes solving problems much easier.
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</div>=20
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<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
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<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.theverge.com%2F2024%2F1%2F29%2F24034201%2Famazon-ir= obot-acquisition-over-antitrust-regulator-scrutiny%3Futm_source=3Dtldrnewsl= etter/1/0100018d5a2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/gfQG7I= -CUOibRNToraUiqyhNdUOlq5dm1P7N2cVbVZg=3D338">
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<strong>Amazon abandons $1.4 billio=
n deal to buy Roomba maker iRobot (2 minute read)</strong>
</span>
</a>
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<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
The deal has no path to regulatory appr= oval in the EU.
</span>
</span>
</div>=20
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<table align=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi= dth=3D"100%"><tbody><tr><td class=3D"container" style=3D"padding: 15px 15px= ;">=20
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<span>
<a href=3D"https://tracking.tldrnewsletter.= com/CL0/https:%2F%2Fwww.theverge.com%2F2024%2F1%2F29%2F24054906%2Ftiktok-yo= utube-horizontal-videos-creators%3Futm_source=3Dtldrnewsletter/1/0100018d5a= 2987da-7e6d9381-accb-4cbd-8515-d5cfce63bcef-000000/6br5IgmZ2aJBJ_UfEVoUxTAa= d1xWRspKvjG4SPNALC0=3D338">
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<strong>TikTok goes full YouTube (1=
minute read)</strong>
</span>
</a>
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<span style=3D"font-family: &quot;Helvetica=
Neue&quot;, Helvetica, Arial, Verdana, sans-serif;">
TikTok will boost horizontal videos tha=
t are more than a minute long within 72 hours of posting for creators who h= ave been on the platform for more than three months, as long as the videos = are not ads or from political parties.
</span>
</span>
</div>=20
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